(Senior) Director Translational Medicine // (Senior) Translational Medicine Expert (m/f/d)

Location: Heidelberg, Germany (Hybrid)

Start Date: Immediate

Responsibilities

• Develop preclinical and early clinical pharmacology strategies for large molecule drug candidates (ADCs and TCEs) at VERAXA Biotech GmbH.
• Lead all early-stage pharmacology and toxicology activities across our pipeline programs.
• Translate program needs into actionable work packages and project plans.
• Endorse, plan, coordinate, execute, and monitor pharmacology/toxicology activities at CROs, ensuring adherence to scope, budget, timeline, and quality expectations.
• Collaborate closely with Program Leaders, the Head of Translational Research, and colleagues from Bioinformatics and Data Sciences.
• Represent pharmacology/toxicology in cross-functional project teams and ensure strategic alignment with ADC and TCE project goals.
• Support indication and patient population selection and contribute to dose and posology decisions up to First-in-Human (FIH) starting dose, through submission and beyond.
• Communicate complex scientific data clearly and concisely to both scientific and cross-functional audiences.
• Establish efficient communication flows, including routine reporting, risk assessments, and project reviews.
• Drive successful achievement of program goals while ensuring alignment with the company’s overall vision and strategic objectives.

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Requirements

• PhD in a relevant field such as preclinical/clinical pharmacology, pharmacometrics, pharmaceutics, statistics, engineering, or mathematics.
• Minimum of 5 years of experience in the(bio)pharmaceutical industry, managing preclinical pharmacology programs and collaborating with CROs for large molecules (e.g., multi-specific antibodies,TCEs, ADCs), ideally up to IND submission.
• Strong understanding of clinical development strategies, including regulatory and quality requirements in GxP environments.
• In-depth knowledge of PK/PD modeling, ADME, posology, and translational quantitative sciences.
• Solid grounding in safety pharmacology, toxicokinetics, and toxicology.
• General understanding of oncology, immuno-oncology, and/or immunology.
• Hands-on modeling expertise (e.g., pharmacometrics or simulation tools) is considered a strong asset.
• Proven ability to work cross-functionally and influence without authority; ideally experienced in matrix team environments.
• Commitment to fostering a strong quality-driven culture.
• Excellent communication, presentation, and project management skills.
• Fluency in English (spoken and written) is required. German skills are a plus.

Working at VERAXA

Working at VERAXA Biotech is an opportunity to be part of a team that is passionate about making a positive impact on the world. With a focus on innovation and quality, we develop cutting-edge biotherapeutics that have the potential to significantly improve patient outcomes. We are always looking for ambitious and talented people to join us and transform targeted therapies. Flat hierarchies and efficient processes are core to our culture, ensuring that scientific excellence always remains our top priority.

Are you interested?

Please send your application to jobs@veraxa.com

About VERAXA Biotech

At VERAXA, we are building a premier engine for the discovery and development of next-generation antibody-based therapeutics, including bispecific ADCs, bispecific T cell engagers and other innovative formats. Powered by a suite of transformative technologies and guided by rigorous quality-by-design principles, we are rapidly advancing our pipeline of ADCs and proprietary BiTAC formats into clinical development and beyond. VERAXA was founded on scientific breakthroughs made at the European Molecular Biology Laboratory, a world-renowned institution known for pioneering life science research and cutting-edge technologies.